ISP said the crash happened in the westbound lanes of Interstate 80 at Wentworth Avenue, near Lansing, just after 5:15 a.m.
The driver of a BMW lost control and struck a Kia Forte, causing the BMW to become stuck in a traffic lane. A semi then struck the BMW.
The BMW's driver was taken to a local hospital, where they were pronounced dead, ISP said.
The two other drivers were not injured.
ISP said around 8 a.m., the westbound lanes of I-80 were shut down at Interstate 294 southbound and diverted to Interstate 94 northbound.
All lanes reopened around 10 a.m.
ISP did not immediately provide further information.